What medication class is commonly prescribed for heartburn and GERD?

Proton pump inhibitors (PPIs) are a commonly prescribed medication class for managing heartburn and gastroesophageal reflux disease (GERD) because they effectively reduce gastric acid production. By blocking the proton pump in the stomach lining, PPIs significantly decrease the amount of acid that is secreted. This action helps alleviate symptoms associated with heartburn and promotes healing of the esophagus when damaged by acid reflux.

PPIs are often favored for their long-lasting effects compared to other treatments, providing relief for an extended period with once-daily dosing. This makes them a cornerstone of therapy in chronic conditions like GERD, where acid suppression is integral to managing symptoms and preventing complications like esophagitis. The choice of PPIs is also supported by clinical guidelines, highlighting their efficacy in treating these conditions.

While other medication classes like H2 receptor antagonists and antacids can also help manage heartburn and GERD, they may not be as effective for long-term management or for more severe cases. Antacids, for instance, provide immediate but short-term relief, while H2 receptor antagonists can be effective but may have limitations in how long they last compared to PPIs. Prokinetics are used for different indications, focusing more on